Frank undertook his undergraduate studies at the University of Western Australia and has a Master of Education (Merit)  from the University of Sydney. He holds a Doctor of Philosophy from Charles Sturt University and a Specialist Certificate in Neuroscience from the University of Melbourne. His main area of research is Human thermoregulation and fatigue. He has also been a Visiting Professor at the University of Cape Town and Rhodes University, South Africa, and the University of Verona, Italy. More recently he was a Visiting Professor at the Department of Human Evolutionary Biology at Harvard University, Cambridge USA.

He is on the Editorial Board of several international Journals including the Journal of Thermal Biology and is a member of the Physiological Society. He is also a Fellow of Exercise and Sports Science Australia.

Frank has also published over 110 peer reviewed papers, book chapters and numerous conference presentations. Most recently, Frank published a book titled Human Fatigue: Evolution, Health & Performance. In 2016 he was awarded the prestigious Spitfire Memorial Fellowship by the Governor General.