Medical Science

Dr Martin Pal

PhD (Institute for Genetics, University of Cologne, Germany)

Lecturer in Medical Science
Wagga Wagga
Building 288 Room 248

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Martin Pal is an expert in genome editing and CRISPR technology, and has extensive research experience across multiple disease contexts, including metabolic disorders and cancer.

He obtained his PhD in Genetics in 2012 from one of the leading institutes in gene targeting technologies, and following a move to Australia in 2013, he has since performed postdoctoral research at four of Australia’s preeminent Medical Research Institutes:

  • John Curtin School of Medical Research at the Australian National University, Canberra (2021)
  • Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne (2016-2021)
  • Garvan Institute of Medical Research, Sydney (2015-2016)
  • Baker Heart and Diabetes Institute, Melbourne (2013-2015)

During his time at WEHI, Martin was part of the Melbourne Advanced Genome Editing Centre (MAGEC), applying CRISPR-Cas9 technology for disease modelling and research into cell death and blood cancers.

Most of his original research work includes specifically generated disease models targeting diverse pathological contexts, which has resulted in multiple high-impact publications.

Martin joined the School of Dentistry and Medical Sciences in August 2021 and is currently setting up his research activities at the School.

Martin Pal is an enthusiastic science educator striving to create an environment where students can flourish. In his teaching he utilizes his extensive background in science, genome editing and disease research to guide students through basic concepts in science.

He is passionate about breaking down complex scientific and molecular technologies into easily understandable information and has developed a growing portfolio of online educational resources showcasing advanced technologies, such as genome editing with CRISPR.

Martin is driven to foster a skillset within undergraduate and HDR students that helps them to succeed in their studies and future career stages.

He is currently teaching within the Medical Sciences subjects, including Molecular Pathology, Molecular and Cellular Biology, and Microbiology.

Martin’s overall research theme is to investigate origins of disease with the ultimate aim of finding novel therapeutic avenues. His research utilizes innovative and advanced genome editing techniques, including CRISPR-Cas technology.

Current Research Interests:

  • Generation of precise genetic model systems by using CRISPR-Cas9 technology in vitro and in vivo
  • Performing whole genome screens to identify novel cancer-driving mutations using traditional CRISPR-Cas9 KO technology, and innovative CRISPR base editing and CRISPR transactivation technology
  • Developing CRISPR diagnostic tools for quick and reliable detection of pathogens

Research grants:

  • Chief Investigator E, Ideas Grant, NHMRC, 2021-2024
  • Postdoctoral Association Professional Development Award, WEHI, 2021
  • Postdoctoral Association Travel Award, WEHI, 2018
  • Research Fellowship Grant, Germany Research Foundation (DFG), 2014-2016
  • Early Career Project Grant, Baker Heart and Diabetes Institute, 2014
  • Honorary Research Associate, Walter and Eliza Hall Institute of Medical Research (WEHI), Parkville, Australia
  • Biochemical Society, Member
  • Royal Society of Biology, Committee Member Australasian Branch

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