After graduating from Charles Sturt with in 2012, Clayton spent 11 years in mixed clinical practice in Narrandera, Leeton and Wagga Wagga. He has a passion for working outside with large animals with a particular focus on reproduction.

In 2023, Clayton undertook and passed his Australian and New Zealand College of Veterinary Scientists Membership exams in Animal Reproduction.

While in practice, Clayton enjoyed having undergraduate students and new graduates to teach and has made the move into the teaching sphere by lecturing in Equine Science.